InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KIF21B

Summary

InnateDB Protein

IDBP-389863.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KIF21B

Protein Name

kinesin family member 21B

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000411831

InnateDB Gene

IDBG-105683 (KIF21B)

Protein Structure

UniProt Annotation

Function

Microtubule-binding motor protein probably involved in neuronal dendritic transport. In vitro, has a plus-end directed motor activity (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008017	microtubule binding

Biological Process

GO:0007018	microtubule-based movement
GO:0008152	metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005871	kinesin complex
GO:0005874	microtubule

Protein Structure and Domains

PDB ID

InterPro

IPR001680 WD40 repeat
IPR001752 Kinesin, motor domain
IPR009053 Prefoldin
IPR010310 Type VII secretion system ESAT-6-like
IPR017986 WD40-repeat-containing domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00400
PF00225
PF06013

PRINTS

PR00380

PIRSF

SMART

SM00320
SM00129

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt