InnateDB Protein
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IDBP-39084.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CEP120
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Protein Name
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centrosomal protein 120kDa
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000327504
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InnateDB Gene
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IDBG-39078 (CEP120)
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Protein Structure
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Function |
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000008
C2 domain
IPR022136
Domain of unknown function DUF3668
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PFAM |
PF00168
PF12416
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PRINTS |
PR00360
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PIRSF |
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SMART |
SM00239
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N960
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PhosphoSite |
PhosphoSite-Q8N960
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TrEMBL |
F8VRV0
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UniProt Splice Variant |
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Entrez Gene |
153241
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UniGene |
Hs.640322
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RefSeq |
NP_694955
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HUGO |
HGNC:26690
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OMIM |
613446
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CCDS |
CCDS4134
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HPRD |
08769
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IMGT |
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EMBL |
AC010369
AC106792
AK093409
AK095646
AL833929
BC040527
BX648687
CR627324
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GenPept |
BAC04155
BAC04596
CAD38785
CAH10371
CAH10561
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