InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ddah1

Summary

InnateDB Protein

IDBP-400346.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ddah1

Protein Name

dimethylarginine dimethylaminohydrolase 1

Synonyms

2410006N07Rik; 2510015N06Rik; AI987801; AW050362;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112747

InnateDB Gene

IDBG-198715 (Ddah1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008270	zinc ion binding
GO:0016403	dimethylargininase activity
GO:0016597	amino acid binding
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

Biological Process

GO:0000052	citrulline metabolic process
GO:0006525	arginine metabolic process
GO:0006809	nitric oxide biosynthetic process
GO:0017014	protein nitrosylation
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0045766	positive regulation of angiogenesis

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:1916469

InterPro

IPR003198 Amidinotransferase

PFAM

PF02274

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YU15

UniProt Splice Variant

Entrez Gene

69219

UniGene

Mm.234247

RefSeq

MGI ID

MGI Symbol

Ddah1

OMIM

CCDS

HPRD

IMGT

EMBL

AC123684 AC126412 CH466532

GenPept

EDL11993