Version 5.4
Mus musculus Protein: Sept8
Summary
InnateDB Protein IDBP-400585.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sept8
Protein Name septin 8
Synonyms AW046166; mKIAA0202; Sepl;
Species Mus musculus
Ensembl Protein ENSMUSP00000112920
InnateDB Gene IDBG-171841 (Sept8)
Protein Structure
UniProt Annotation
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity). {ECO:0000250, ECO:0000305}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0007049 cell cycle
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0031105 septin complex
Protein Structure and Domains
PDB ID MGI:894310
InterPro IPR000038 Cell division protein GTP binding
IPR016491 Septin
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00735
PRINTS
PIRSF PIRSF006698
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CHH9
PhosphoSite PhosphoSite-Q8CHH9
TrEMBL E0CYM4
UniProt Splice Variant
Entrez Gene 20362
UniGene Mm.409093
RefSeq NP_149156
MGI ID
MGI Symbol Sept8
OMIM
CCDS CCDS48794
HPRD
IMGT
EMBL AB093215 AF179996 AL596095 BC049819 BC059248
GenPept AAG09408 AAH49819 AAH59248 BAC41399 CAP19145

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca