InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spock2

Summary

InnateDB Protein

IDBP-401298.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Spock2

Protein Name

sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2

Synonyms

AA407235; Gcap26; mKIAA0275;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113115

InnateDB Gene

IDBG-154392 (Spock2)

Protein Structure

UniProt Annotation

Function

May participate in diverse steps of neurogenesis. Binds calcium (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted, extracellular space, extracellular matrix {ECO:0000305}.

Disease Associations

Tissue Specificity

Brain specific.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005539	glycosaminoglycan binding
GO:0050840	extracellular matrix binding

Biological Process

GO:0007165	signal transduction
GO:0010811	positive regulation of cell-substrate adhesion
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0030198	extracellular matrix organization