InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hspa8

Summary

InnateDB Protein

IDBP-401319.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hspa8

Protein Name

heat shock protein 8

Synonyms

2410008N15Rik; Hsc70; Hsc71; Hsc73; Hsp73; Hspa10;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113722

InnateDB Gene

IDBG-153613 (Hspa8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 79 experimentally validated interaction(s) in this database.
They are also associated with 255 interaction(s) predicted by orthology.

Experimentally validated
Total	79 [view]
Protein-Protein	79 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	255 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0042623	ATPase activity, coupled
GO:0051082	unfolded protein binding

Biological Process

GO:0000902	cell morphogenesis
GO:0006200	ATP catabolic process
GO:0006457	protein folding
GO:0045892	negative regulation of transcription, DNA-templated
GO:0051085	chaperone mediated protein folding requiring cofactor
GO:0051726	regulation of cell cycle
GO:0072318	clathrin coat disassembly

Cellular Component

GO:0000974	Prp19 complex
GO:0005622	intracellular
GO:0005730	nucleolus
GO:0005829	cytosol
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:105384

InterPro

IPR004753 Cell shape determining protein MreB/Mrl
IPR013126 Heat shock protein 70 family
IPR029047 Heat shock protein 70kD, peptide-binding domain
IPR029048 Heat shock protein 70kD, C-terminal domain

PFAM

PF06723
PF00012

PRINTS

PR01652
PR00301

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9QZ38

UniProt Splice Variant

Entrez Gene

15481

UniGene

Mm.472965

RefSeq

MGI ID

MGI Symbol

Hspa8

OMIM

CCDS

HPRD

IMGT

EMBL

AC158355 AK135281 AK150846 BC094900 X05837

GenPept

AAH94900 BAE22472 BAE29904 CAB57815