Version 5.4
Homo sapiens Protein: ADAT1
Summary
InnateDB Protein IDBP-42669.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAT1
Protein Name adenosine deaminase, tRNA-specific 1
Synonyms HADAT1;
Species Homo sapiens
Ensembl Protein ENSP00000310015
InnateDB Gene IDBG-42667 (ADAT1)
Protein Structure
UniProt Annotation
Function Specifically deaminates adenosine-37 to inosine in tRNA- Ala.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:10430867}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004000 adenosine deaminase activity
GO:0008251 tRNA-specific adenosine deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0008033 tRNA processing
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002466 Adenosine deaminase/editase
PFAM PF02137
PRINTS
PIRSF
SMART SM00552
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BUB4
PhosphoSite PhosphoSite-Q9BUB4
TrEMBL H3BU72
UniProt Splice Variant
Entrez Gene 23536
UniGene Hs.729312
RefSeq NP_036223
HUGO HGNC:228
OMIM 604230
CCDS CCDS10922
HPRD 11970
IMGT
EMBL AC025287 AF125188 AK001687 BC002758
GenPept AAD48376 AAH02758 BAA91837

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca