Version 5.4
Homo sapiens Gene: ADAT1
Summary
InnateDB Gene IDBG-42667.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAT1
Gene Name adenosine deaminase, tRNA-specific 1
Synonyms HADAT1
Species Homo sapiens
Ensembl Gene ENSG00000065457
Encoded Proteins
IDBP-42669
adenosine deaminase, tRNA-specific 1
IDBP-753536
IDBP-749340
IDBP-745630
IDBP-752009
IDBP-746998
IDBP-747392
IDBP-747709
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:75596981-75623300
Strand Reverse strand
Band q23.1
Transcripts
ENST00000307921 ENSP00000310015
ENST00000568001 ENSP00000457999
ENST00000565109
ENST00000568510 ENSP00000455000
ENST00000566445 ENSP00000456768
ENST00000564657 ENSP00000457501
ENST00000568478
ENST00000566450 ENSP00000455121
ENST00000567281 ENSP00000455108
ENST00000562374 ENSP00000456751
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004000 adenosine deaminase activity
GO:0008251 tRNA-specific adenosine deaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0006396 RNA processing
GO:0008033 tRNA processing
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031949
View Gene Order
ENSBTAG00000015669
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.729312
RefSeq NM_012091
HUGO
OMIM
CCDS CCDS10922
HPRD 11970
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca