InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LUC7L2

Summary

InnateDB Protein

IDBP-43654.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LUC7L2

Protein Name

LUC7-like 2 (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000347005

InnateDB Gene

IDBG-43650 (LUC7L2)

Protein Structure

UniProt Annotation

Function

May bind to RNA via its Arg/Ser-rich domain.

Subcellular Localization

Nucleus speckle {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000250}. Note=Colocalizes with SCNM1 and SNRNP70 in nuclear speckles. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 111 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	111 [view]
Protein-Protein	110 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006376

mRNA splice site selection

Cellular Component

GO:0005685	U1 snRNP
GO:0016607	nuclear speck

Protein Structure and Domains

PDB ID

InterPro

IPR004882 Luc7-related

PFAM

PF03194

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Y383

PhosphoSite

PhosphoSite-Q9Y383

TrEMBL

B3KSP8

UniProt Splice Variant

Entrez Gene

51631

UniGene

Hs.740446

RefSeq

NP_057103

HUGO

HGNC:44671

OMIM

613056

CCDS

CCDS43656

HPRD

17456

IMGT

EMBL

AF151817 AF151832 AK001476 AK001519 AK022895 AK094081 AK298166 BC017163 BC042625 BC050708 BC056886

GenPept

AAD34054 AAD34069 AAH17163 AAH42625 AAH50708 AAH56886 BAA91713 BAA91737 BAB14297 BAG52810 BAH12736