Version 5.4
Homo sapiens Gene: LUC7L2
Summary
InnateDB Gene IDBG-43650.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LUC7L2
Gene Name LUC7-like 2 (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146963
Encoded Proteins
IDBP-43652
LUC7-like 2 (S. cerevisiae)
IDBP-43654
LUC7-like 2 (S. cerevisiae)
IDBP-386778
LUC7-like 2 (S. cerevisiae)
IDBP-598567
LUC7-like 2 (S. cerevisiae)
IDBP-588911
LUC7-like 2 (S. cerevisiae)
IDBP-813441
C7orf55-LUC7L2 readthrough
IDBP-813447
C7orf55-LUC7L2 readthrough
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring readthrough transcription between the neighboring C7orf55 (chromosome 7 open reading frame 55) and LUC7L2 (LUC7-like 2) genes on chromosome 7. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jul 2012] This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:139340359-139423457
Strand Forward strand
Band q34
Transcripts
ENST00000263545 ENSP00000263545
ENST00000354926 ENSP00000347005
ENST00000435096
ENST00000456182 ENSP00000393012
ENST00000463912
ENST00000498518
ENST00000482860
ENST00000541515 ENSP00000440222
ENST00000541170 ENSP00000441604
ENST00000608368 ENSP00000477492
ENST00000619796 ENSP00000483438
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 111 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 111 [view]
Protein-Protein 110 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006376 mRNA splice site selection
Cellular Component
GO:0005685 U1 snRNP
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029823
View Gene Order
ENSBTAG00000017770
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.370475 Hs.627960 Hs.740446
RefSeq NM_001244585 NM_001270643 NM_016019 NM_001244584
HUGO
OMIM
CCDS CCDS43656 CCDS59085 CCDS59510 CCDS59084
HPRD 17456
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca