Version 5.4
Homo sapiens Protein: CAMLG
Summary
InnateDB Protein IDBP-45077.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAMLG
Protein Name calcium modulating ligand
Synonyms CAML;
Species Homo sapiens
Ensembl Protein ENSP00000297156
InnateDB Gene IDBG-45075 (CAMLG)
Protein Structure
UniProt Annotation
Function Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Ubiquitous. Highest levels in brain, testis and ovary.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 12 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0001881 receptor recycling
GO:0006952 defense response
GO:0007165 signal transduction
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0016032 viral process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR016719 Calcium signal-modulating cyclophilin ligand
PFAM
PRINTS
PIRSF PIRSF018259
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49069
PhosphoSite PhosphoSite-P49069
TrEMBL
UniProt Splice Variant
Entrez Gene 819
UniGene Hs.600007
RefSeq NP_001736
HUGO HGNC:1471
OMIM 601118
CCDS CCDS4178
HPRD 03073
IMGT
EMBL AF068179 AK313156 BC130325 CH471062 U18242
GenPept AAA59420 AAC23596 AAI30326 BAG35974 EAW62243 EAW62244

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca