Version 5.4
Homo sapiens Protein: ANXA6
Summary
InnateDB Protein IDBP-473416.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANXA6
Protein Name annexin A6
Synonyms ANX6; CBP68;
Species Homo sapiens
Ensembl Protein ENSP00000430517
InnateDB Gene IDBG-54213 (ANXA6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 32 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0005544 calcium-dependent phospholipid binding
GO:0008289 lipid binding
GO:0015276 ligand-gated ion channel activity
GO:0015485 cholesterol binding
GO:0042803 protein homodimerization activity
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0034220 ion transmembrane transport
GO:0051260 protein homooligomerization
Cellular Component
GO:0005765 lysosomal membrane
GO:0016020 membrane
GO:0031902 late endosome membrane
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001464 Annexin
IPR002391 Annexin, type IV
IPR002393 Annexin, type VI
IPR018502 Annexin repeat
PFAM PF00191
PRINTS PR00196
PR00200
PR00202
PIRSF
SMART SM00335
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08133
PhosphoSite PhosphoSite-P08133
TrEMBL E5RK63
UniProt Splice Variant
Entrez Gene 309
UniGene Hs.412117
RefSeq NP_001180473
HUGO HGNC:544
OMIM 114070
CCDS CCDS54941
HPRD 00231
IMGT
EMBL AC008641 AK126836 AK298582 AK303078 BC017046 CH471062 D00510 J03578 Y00097
GenPept AAA35656 AAH17046 BAA00400 BAC86715 BAH12818 BAH13893 CAA68286 EAW61684 EAW61686

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca