Version 5.4
Homo sapiens Protein: DROSHA
Summary
InnateDB Protein IDBP-474862.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DROSHA
Protein Name drosha, ribonuclease type III
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000428782
InnateDB Gene IDBG-14255 (DROSHA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 55 experimentally validated interaction(s) in this database.
Experimentally validated
Total 55 [view]
Protein-Protein 54 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0016075 rRNA catabolic process
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YB67
UniProt Splice Variant
Entrez Gene 29102
UniGene Hs.97997
RefSeq
HUGO HGNC:17904
OMIM 608828
CCDS
HPRD 10196
IMGT
EMBL AC008768 AC022417 AC106802
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca