Version 5.4
Homo sapiens Protein: HPSE
Summary
InnateDB Protein IDBP-477346.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HPSE
Protein Name heparanase
Synonyms HPA; HPA1; HPR1; HPSE1; HSE1;
Species Homo sapiens
Ensembl Protein ENSP00000426139
InnateDB Gene IDBG-27684 (HPSE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR005199 Glycoside hydrolase, family 79
IPR017853 Glycoside hydrolase, superfamily
PFAM PF03662
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RHG4
UniProt Splice Variant
Entrez Gene 10855
UniGene Hs.627092
RefSeq
HUGO HGNC:5164
OMIM 604724
CCDS
HPRD 05286
IMGT
EMBL AC114781
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca