InnateDB Protein
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IDBP-477629.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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INTS8
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Protein Name
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integrator complex subunit 8
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000430338
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InnateDB Gene
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IDBG-29133 (INTS8)
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Protein Structure
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Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
11
[view]
|
Protein-Protein |
11
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q75QN2
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PhosphoSite |
PhosphoSite-Q75QN2
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TrEMBL |
E5RJL5
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UniProt Splice Variant |
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Entrez Gene |
55656
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UniGene |
Hs.727669
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RefSeq |
NP_060334
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HUGO |
HGNC:26048
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OMIM |
611351
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CCDS |
CCDS34925
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HPRD |
08626
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IMGT |
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EMBL |
AB161944
AK000537
AK001403
AK091278
AP003692
BC050536
BC064915
BC136754
BK005731
BX538203
CH471060
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GenPept |
AAH50536
AAH64915
AAI36755
BAA91238
BAA91671
BAD10863
BAG52322
CAD98067
DAA05731
EAW91726
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