InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HTR4

Summary

InnateDB Protein

IDBP-479253.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HTR4

Protein Name

5-hydroxytryptamine (serotonin) receptor 4

Synonyms

5-HT4; 5-HT4R;

Species

Homo sapiens

Ensembl Protein

ENSP00000430451

InnateDB Gene

IDBG-52561 (HTR4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004993	serotonin receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007210	serotonin receptor signaling pathway
GO:0007268	synaptic transmission
GO:0032098	regulation of appetite

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001520 5-Hydroxytryptamine 4 receptor
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR01059

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E5RK45

UniProt Splice Variant

Entrez Gene

3360

UniGene

Hs.483773

RefSeq

HUGO

HGNC:5299

OMIM

602164

CCDS

HPRD

IMGT

EMBL

AC008627 AC011390 AC091971 AC114939

GenPept