InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ABCB8

Summary

InnateDB Protein

IDBP-479722.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCB8

Protein Name

ATP-binding cassette, sub-family B (MDR/TAP), member 8

Synonyms

EST328128; M-ABC1; MABC1;

Species

Homo sapiens

Ensembl Protein

ENSP00000418271

InnateDB Gene

IDBG-48655 (ABCB8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Experimentally validated
Total	12 [view]
Protein-Protein	10 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0043190	ATP-binding cassette (ABC) transporter complex

Protein Structure and Domains

PDB ID

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NUT2