Version 5.4
Homo sapiens Protein: ABCB8
Summary
InnateDB Protein IDBP-479869.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCB8
Protein Name ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms EST328128; M-ABC1; MABC1;
Species Homo sapiens
Ensembl Protein ENSP00000419558
InnateDB Gene IDBG-48655 (ABCB8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 10 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001140 ABC transporter, transmembrane domain
IPR011527 ABC transporter type 1, transmembrane domain
PFAM PF00664
PF13748
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JTY4
UniProt Splice Variant
Entrez Gene 11194
UniGene Hs.735539
RefSeq
HUGO HGNC:49
OMIM 605464
CCDS
HPRD 10400
IMGT
EMBL AC010973 CH471173
GenPept EAW54058

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca