InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DDX4

Summary

InnateDB Protein

IDBP-479996.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DDX4

Protein Name

DEAD (Asp-Glu-Ala-Asp) box polypeptide 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000425359

InnateDB Gene

IDBG-21276 (DDX4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0007275	multicellular organismal development
GO:0030317	sperm motility

Cellular Component

GO:0005737	cytoplasm
GO:0048471	perinuclear region of cytoplasm
GO:0071546	pi-body
GO:0071547	piP-body

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR011545 DEAD/DEAH box helicase domain
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF00270

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NQI0