InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: F2RL1

Summary

InnateDB Protein

IDBP-480110.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

F2RL1

Protein Name

coagulation factor II (thrombin) receptor-like 1

Synonyms

GPR11; PAR2;

Species

Homo sapiens

Ensembl Protein

ENSP00000425622

InnateDB Gene

IDBG-29713 (F2RL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0015057	thrombin receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0070493	thrombin receptor signaling pathway

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR002281 Protease-activated receptor 2
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR01152

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D6RJH3

UniProt Splice Variant

Entrez Gene

2150

UniGene

Hs.743692

RefSeq

HUGO

HGNC:3538

OMIM

600933

CCDS

HPRD

02960

IMGT

EMBL

AC010621

GenPept