InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GC

Summary

InnateDB Protein

IDBP-481138.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Protein Name

group-specific component (vitamin D binding protein)

Synonyms

DBP; DBP/GC; GRD3; HEL-S-51; VDBG; VDBP;

Species

Homo sapiens

Ensembl Protein

ENSP00000421725

InnateDB Gene

IDBG-23016 (GC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.

Experimentally validated
Total	22 [view]
Protein-Protein	22 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005499	vitamin D binding
GO:0051183	vitamin transporter activity
GO:1902118	calcidiol binding

Biological Process

GO:0008202	steroid metabolic process
GO:0042359	vitamin D metabolic process
GO:0044281	small molecule metabolic process
GO:0051180	vitamin transport

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005829	cytosol
GO:0043202	lysosomal lumen
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR000213 Vitamin D-binding protein
IPR000264 ALB/AFP/VDB
IPR014760 Serum albumin, N-terminal
IPR015247 Vitamin D binding protein, domain III
IPR020858 Serum albumin-like

PFAM

PF00273
PF09164

PRINTS

PR00804
PR00802

PIRSF

SMART

SM00103

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt