InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP6V1F

Summary

InnateDB Protein

IDBP-482020.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP6V1F

Protein Name

ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F

Synonyms

ATP6S14; VATF; Vma7;

Species

Homo sapiens

Ensembl Protein

ENSP00000417378

InnateDB Gene

IDBG-40301 (ATP6V1F)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0042624	ATPase activity, uncoupled
GO:0042625	ATPase activity, coupled to transmembrane movement of ions
GO:0046961	proton-transporting ATPase activity, rotational mechanism

Biological Process

GO:0006200	ATP catabolic process
GO:0006879	cellular iron ion homeostasis
GO:0008286	insulin receptor signaling pathway
GO:0015991	ATP hydrolysis coupled proton transport
GO:0015992	proton transport
GO:0033572	transferrin transport
GO:0034220	ion transmembrane transport
GO:0051701	interaction with host
GO:0055085	transmembrane transport
GO:0090382	phagosome maturation

Cellular Component

GO:0005829	cytosol
GO:0016020	membrane
GO:0016469	proton-transporting two-sector ATPase complex
GO:0016471	vacuolar proton-transporting V-type ATPase complex
GO:0033180	proton-transporting V-type ATPase, V1 domain
GO:0070062	extracellular vesicular exosome