InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOXB3

Summary

InnateDB Protein

IDBP-483039.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOXB3

Protein Name

homeobox B3

Synonyms

Hox-2.7; HOX2; HOX2G;

Species

Homo sapiens

Ensembl Protein

ENSP00000420595

InnateDB Gene

IDBG-56791 (HOXB3)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0001525	angiogenesis
GO:0006351	transcription, DNA-templated

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa

PFAM

PF00046

PRINTS

PR00024

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P14651

PhosphoSite

PhosphoSite-P14651

TrEMBL

C9J2I3

UniProt Splice Variant

Entrez Gene

3213

UniGene

Hs.687723

RefSeq

XP_005257334

HUGO

HGNC:5114

OMIM

142966

CCDS

CCDS11528

HPRD

00853

IMGT

EMBL

AC103702 AF287967 AK291182 AK299226 AK315102 AK316245 CH471109 U59298 X16175 X16667

GenPept

AAD10852 AAG31555 BAF83871 BAG37563 BAH12974 BAH14616 CAA34297 CAA34657 EAW94739 EAW94740 EAW94741