Version 5.4
Homo sapiens Protein: CNOT8
Summary
InnateDB Protein IDBP-483709.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNOT8
Protein Name CCR4-NOT transcription complex, subunit 8
Synonyms CAF1; Caf1b; CALIF; hCAF1; POP2;
Species Homo sapiens
Ensembl Protein ENSP00000431034
InnateDB Gene IDBG-55066 (CNOT8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 22 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006941 Ribonuclease CAF1
IPR012337 Ribonuclease H-like domain
PFAM PF04857
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RIU0
UniProt Splice Variant
Entrez Gene 9337
UniGene Hs.740031
RefSeq NP_001288015
HUGO HGNC:9207
OMIM 603731
CCDS
HPRD 07225
IMGT
EMBL AC112169 AK297381 AK315864 AK316055 AK316221 AK316269
GenPept BAF98755 BAH12567 BAH14426 BAH14592 BAH14640

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca