Homo sapiens Protein: CDH12
Summary
InnateDB Protein IDBP-484151.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDH12
Protein Name cadherin 12, type 2 (N-cadherin 2)
Synonyms CDHB;
Species Homo sapiens
Ensembl Protein ENSP00000423577
InnateDB Gene IDBG-13717 (CDH12)
Protein Structure
UniProt Annotation
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular Localization Cell membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0034329 cell junction assembly
GO:0034332 adherens junction organization
GO:0045216 cell-cell junction organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR015919 Cadherin-like
PFAM PF01049
PF00028
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P55289
PhosphoSite PhosphoSite-P55289
TrEMBL B3KRT0
UniProt Splice Variant
Entrez Gene 1010
UniGene Hs.113684
RefSeq
HUGO HGNC:1751
OMIM 600562
CCDS CCDS3890
HPRD 11081
IMGT
EMBL AK092176 AK314800 BC047608 CH471118 L33477 L34057
GenPept AAA35623 AAB48539 AAH47608 BAG37328 BAG52492 EAX10736