InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HOXB3

Summary

InnateDB Protein

IDBP-485092.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HOXB3

Protein Name

homeobox B3

Synonyms

Hox-2.7; HOX2; HOX2G;

Species

Homo sapiens

Ensembl Protein

ENSP00000417207

InnateDB Gene

IDBG-56791 (HOXB3)

Protein Structure

UniProt Annotation

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001525	angiogenesis
GO:0002244	hematopoietic progenitor cell differentiation
GO:0006351	transcription, DNA-templated
GO:0009952	anterior/posterior pattern specification
GO:0021546	rhombomere development
GO:0021615	glossopharyngeal nerve morphogenesis
GO:0030878	thyroid gland development
GO:0048704	embryonic skeletal system morphogenesis
GO:0050767	regulation of neurogenesis
GO:0051216	cartilage development
GO:0060216	definitive hemopoiesis
GO:0060324	face development