Version 5.4
Homo sapiens Protein: BRAF
Summary
InnateDB Protein IDBP-485293.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRAF
Protein Name v-raf murine sarcoma viral oncogene homolog B1
Synonyms B-RAF1; BRAF1; NS7; RAFB1;
Species Homo sapiens
Ensembl Protein ENSP00000420119
InnateDB Gene IDBG-44351 (BRAF)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 70 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 70 [view]
Protein-Protein 69 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
Biological Process
GO:0007165 signal transduction
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003116 Raf-like Ras-binding
IPR029071 Ubiquitin-related domain
PFAM PF02196
PRINTS
PIRSF
SMART SM00455
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C5K3
UniProt Splice Variant
Entrez Gene 673
UniGene Hs.613773
RefSeq
HUGO HGNC:1097
OMIM 164757
CCDS
HPRD 01264
IMGT
EMBL AC006006 AC006344 AC006347 AC079339
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca