InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SH3KBP1

Summary

InnateDB Protein

IDBP-49940.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SH3KBP1

Protein Name

SH3-domain kinase binding protein 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000369039

InnateDB Gene

IDBG-49936 (SH3KBP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 306 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	306 [view]
Protein-Protein	304 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016301	kinase activity
GO:0017124	SH3 domain binding

Biological Process

GO:0006897	endocytosis
GO:0006915	apoptotic process
GO:0007010	cytoskeleton organization
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007267	cell-cell signaling
GO:0008360	regulation of cell shape
GO:0016310	phosphorylation
GO:0016477	cell migration
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway

Cellular Component

GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0005925	focal adhesion
GO:0030659	cytoplasmic vesicle membrane
GO:0043005	neuron projection
GO:0045202	synapse