InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NTS

Summary

InnateDB Protein

IDBP-50025.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NTS

Protein Name

neurotensin

Synonyms

NMN-125; NN; NT; NT/N; NTS1;

Species

Homo sapiens

Ensembl Protein

ENSP00000256010

InnateDB Gene

IDBG-50023 (NTS)

Protein Structure

UniProt Annotation

Function

Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

Subcellular Localization

Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005184	neuropeptide hormone activity
GO:0005515	protein binding

Biological Process

GO:0007165	signal transduction
GO:0050880	regulation of blood vessel size

Cellular Component

GO:0005576	extracellular region
GO:0030133	transport vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR008055 Neurotensin/neuromedin N

PFAM

PF07421

PRINTS

PR01668

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P30990

PhosphoSite

PhosphoSite-P30990

TrEMBL

Q86U50

UniProt Splice Variant

Entrez Gene

4922

UniGene

RefSeq

NP_006174

HUGO

HGNC:8038

OMIM

162650

CCDS

CCDS9029

HPRD

08878

IMGT

EMBL

AF157682 AF157683 AK312066 BC010918 CH471054 CR541936 S47339 U91618

GenPept

AAB23934 AAB50564 AAH10918 AAP37614 AAP37615 BAG35002 CAG46734 EAW97401