InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PIGF

Summary

InnateDB Protein

IDBP-50454.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIGF

Protein Name

phosphatidylinositol glycan anchor biosynthesis, class F

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000281382

InnateDB Gene

IDBG-50448 (PIGF)

Protein Structure

UniProt Annotation

Function

Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	0
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004307	ethanolaminephosphotransferase activity

Biological Process

GO:0006501	C-terminal protein lipidation
GO:0006506	GPI anchor biosynthetic process
GO:0016254	preassembly of GPI anchor in ER membrane
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process