InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC3A2

Summary

InnateDB Protein

IDBP-52054.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC3A2

Protein Name

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

Synonyms

4F2; 4F2HC; 4T2HC; CD98; CD98HC; MDU1; NACAE;

Species

Homo sapiens

Ensembl Protein

ENSP00000367123

InnateDB Gene

IDBG-52050 (SLC3A2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	43 [view]
Protein-Protein	41 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0015175	neutral amino acid transmembrane transporter activity
GO:0043169	cation binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0008152	metabolic process
GO:0015804	neutral amino acid transport
GO:0060356	leucine import

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0030054	cell junction

Protein Structure and Domains

PDB ID

InterPro

IPR006047 Glycosyl hydrolase, family 13, catalytic domain
IPR006589 Glycosyl hydrolase, family 13, subfamily, catalytic domain
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF00128

PRINTS

PIRSF

SMART

SM00642

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite