InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPS6

Summary

InnateDB Protein

IDBP-52820.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS6

Protein Name

ribosomal protein S6

Synonyms

S6;

Species

Homo sapiens

Ensembl Protein

ENSP00000369757

InnateDB Gene

IDBG-52818 (RPS6)

Protein Structure

UniProt Annotation

Function

May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 201 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	201 [view]
Protein-Protein	198 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000028	ribosomal small subunit assembly
GO:0000082	G1/S transition of mitotic cell cycle
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001890	placenta development
GO:0002309	T cell proliferation involved in immune response
GO:0006364	rRNA processing
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0006924	activation-induced cell death of T cells
GO:0007067	mitotic nuclear division
GO:0007093	mitotic cell cycle checkpoint
GO:0007369	gastrulation
GO:0008286	insulin receptor signaling pathway
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0022605	oogenesis stage
GO:0031929	TOR signaling
GO:0033077	T cell differentiation in thymus
GO:0042274	ribosomal small subunit biogenesis
GO:0042593	glucose homeostasis
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0044267	cellular protein metabolic process
GO:0048821	erythrocyte development

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005844	polysome
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022627	cytosolic small ribosomal subunit
GO:0030425	dendrite
GO:0030529	ribonucleoprotein complex
GO:0036464	cytoplasmic ribonucleoprotein granule
GO:0044297	cell body
GO:0048471	perinuclear region of cytoplasm