InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STIP1

Summary

InnateDB Protein

IDBP-53110.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STIP1

Protein Name

stress-induced-phosphoprotein 1

Synonyms

HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L;

Species

Homo sapiens

Ensembl Protein

ENSP00000305958

InnateDB Gene

IDBG-53106 (STIP1)

Protein Structure

UniProt Annotation

Function

Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).

Subcellular Localization

Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 106 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	106 [view]
Protein-Protein	106 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006950

response to stress

Cellular Component

GO:0005634	nucleus
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

InterPro

IPR001440 Tetratricopeptide TPR1
IPR006636 Heat shock chaperonin-binding
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00727
SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P31948