InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Syt1

Summary

InnateDB Protein

IDBP-532135.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Syt1

Protein Name

synaptotagmin I

Synonyms

AW124717; G630098F17Rik; SytI;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116981

InnateDB Gene

IDBG-189557 (Syt1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005544	calcium-dependent phospholipid binding
GO:0050750	low-density lipoprotein particle receptor binding

Biological Process

GO:0007269	neurotransmitter secretion
GO:0016079	synaptic vesicle exocytosis

Cellular Component

GO:0008021	synaptic vesicle
GO:0030141	secretory granule
GO:0030672	synaptic vesicle membrane
GO:0042734	presynaptic membrane
GO:0043005	neuron projection

Protein Structure and Domains

PDB ID

MGI:99667

InterPro

IPR000008 C2 domain
IPR001565 Synaptotagmin

PFAM

PF00168

PRINTS

PR00360
PR00399

PIRSF

SMART

SM00239

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z7R4

UniProt Splice Variant

Entrez Gene

20979

UniGene

Mm.399963

RefSeq

MGI ID

MGI Symbol

Syt1

OMIM

CCDS

HPRD

IMGT

EMBL

AC117199 AC122472 AC124436 AC141899 AC162908 AC163645

GenPept