InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fntb

Summary

InnateDB Protein

IDBP-532327.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fntb

Protein Name

farnesyltransferase, CAAX box, beta

Synonyms

2010013E13Rik; AA409500;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120713

InnateDB Gene

IDBG-151393 (Fntb)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004311	farnesyltranstransferase activity
GO:0008270	zinc ion binding

Biological Process

GO:0007275	multicellular organismal development
GO:0008284	positive regulation of cell proliferation
GO:0008285	negative regulation of cell proliferation
GO:0018343	protein farnesylation
GO:0042060	wound healing
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048146	positive regulation of fibroblast proliferation

Cellular Component

GO:0005965

protein farnesyltransferase complex

Protein Structure and Domains

PDB ID

MGI:1861305

InterPro

IPR001330 Prenyltransferase/squalene oxidase
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
IPR009508 Transcription activator, Churchill

PFAM

PF00432
PF06573

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-