InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Abp1

Summary

InnateDB Protein

IDBP-533285.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Abp1

Protein Name

amiloride binding protein 1 (amine oxidase, copper-containing)

Synonyms

1600012D06Rik; Abp1; DAO;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124085

InnateDB Gene

IDBG-145895 (Abp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005261	cation channel activity
GO:0005507	copper ion binding
GO:0008131	primary amine oxidase activity
GO:0008144	drug binding
GO:0008201	heparin binding
GO:0008270	zinc ion binding
GO:0032403	protein complex binding
GO:0048038	quinone binding
GO:0052597	diamine oxidase activity
GO:0052598	histamine oxidase activity
GO:0052599	methylputrescine oxidase activity
GO:0052600	propane-1,3-diamine oxidase activity

Biological Process

GO:0006812	cation transport
GO:0009308	amine metabolic process
GO:0035874	cellular response to copper ion starvation
GO:0042493	response to drug
GO:0046677	response to antibiotic
GO:0055114	oxidation-reduction process
GO:0071280	cellular response to copper ion
GO:0071420	cellular response to histamine
GO:0097185	cellular response to azide

Cellular Component

GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0005923	tight junction

Protein Structure and Domains

PDB ID

MGI:1923757

InterPro

IPR000269 Copper amine oxidase
IPR015798 Copper amine oxidase, C-terminal
IPR015800 Copper amine oxidase, N2-terminal
IPR015802 Copper amine oxidase, N3-terminal
IPR016182 Copper amine oxidase, N-terminal

PFAM

PF01179
PF02727
PF02728

PRINTS

PR00766

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8JZQ5