Version 5.4
Mus musculus Protein: Mcm7
Summary
InnateDB Protein IDBP-533742.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mcm7
Protein Name minichromosome maintenance deficient 7 (S. cerevisiae)
Synonyms AI747533; mCDC47; Mcmd7;
Species Mus musculus
Ensembl Protein ENSMUSP00000116131
InnateDB Gene IDBG-205861 (Mcm7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 107 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 107 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006270 DNA replication initiation
GO:0006974 cellular response to DNA damage stimulus
GO:0008283 cell proliferation
GO:0042325 regulation of phosphorylation
GO:0042493 response to drug
GO:0071364 cellular response to epidermal growth factor stimulus
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0042555 MCM complex
Protein Structure and Domains
PDB ID MGI:1298398
InterPro IPR001208 Mini-chromosome maintenance, DNA-dependent ATPase
IPR008050 DNA replication licensing factor Mcm7
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF00493
PRINTS PR01657
PR01663
PIRSF
SMART SM00350
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z6N3
UniProt Splice Variant
Entrez Gene 17220
UniGene Mm.482227
RefSeq
MGI ID
MGI Symbol Mcm7
OMIM
CCDS
HPRD
IMGT
EMBL AC151719
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca