Version 5.4
Mus musculus Protein: Sqstm1
Summary
InnateDB Protein IDBP-534141.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sqstm1
Protein Name sequestosome 1
Synonyms A170; OSF-6; Osi; p62; STAP; STONE14;
Species Mus musculus
Ensembl Protein ENSMUSP00000118662
InnateDB Gene IDBG-168358 (Sqstm1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 98 experimentally validated interaction(s) in this database.
They are also associated with 172 interaction(s) predicted by orthology.
Experimentally validated
Total 98 [view]
Protein-Protein 98 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 172 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003712 transcription cofactor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
Biological Process
GO:0045087 innate immune response (InnateDB)
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
GO:0000407 pre-autophagosomal structure
GO:0016235 aggresome
Protein Structure and Domains
PDB ID MGI:107931
InterPro IPR000270 Phox/Bem1p
IPR000433 Zinc finger, ZZ-type
PFAM PF00564
PF00569
PRINTS
PIRSF
SMART SM00666
SM00291
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YZJ1
UniProt Splice Variant
Entrez Gene 18412
UniGene Mm.473573
RefSeq
MGI ID
MGI Symbol Sqstm1
OMIM
CCDS
HPRD
IMGT
EMBL AL627187
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca