InnateDB Protein
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IDBP-534896.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Usf1
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Protein Name
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upstream transcription factor 1
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Synonyms
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bHLHb11;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000125729
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InnateDB Gene
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IDBG-204574 (Usf1)
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Protein Structure
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Function |
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
6
[view]
|
Protein-DNA |
7
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
52 [view]
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Molecular Function |
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Biological Process |
GO:0000432
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positive regulation of transcription from RNA polymerase II promoter by glucose
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GO:0001666
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response to hypoxia
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GO:0006006
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glucose metabolic process
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0009411
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response to UV
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GO:0019086
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late viral transcription
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GO:0032869
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cellular response to insulin stimulus
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GO:0045893
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positive regulation of transcription, DNA-templated
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0055088
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lipid homeostasis
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Cellular Component |
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PDB ID |
MGI:99542
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InterPro |
IPR011598
Myc-type, basic helix-loop-helix (bHLH) domain
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PFAM |
PF00010
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PRINTS |
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PIRSF |
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SMART |
SM00353
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TIGRFAMs |
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Modification |
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SwissProt |
Q61069
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PhosphoSite |
PhosphoSite-Q61069
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TrEMBL |
Q8R4E5
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UniProt Splice Variant |
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Entrez Gene |
226654
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UniGene |
Mm.8
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RefSeq |
XP_006496810
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MGI ID |
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MGI Symbol |
Usf1
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OMIM |
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CCDS |
CCDS15495
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HPRD |
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IMGT |
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EMBL |
AC087229
AF479773
AK142437
CH466520
U41741
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GenPept |
AAC52921
AAL87134
BAE25064
EDL39082
EDL39084
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