InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Map4k2

Summary

InnateDB Protein

IDBP-535737.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Map4k2

Protein Name

mitogen-activated protein kinase kinase kinase kinase 2

Synonyms

AI385662; BL44; GCK; Rab8ip;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115741

InnateDB Gene

IDBG-135906 (Map4k2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0005524	ATP binding
GO:0008349	MAP kinase kinase kinase kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000165	MAPK cascade
GO:0000185	activation of MAPKKK activity
GO:0006468	protein phosphorylation
GO:0035556	intracellular signal transduction

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:1346883

InterPro

IPR000719 Protein kinase domain
IPR011009 Protein kinase-like domain

PFAM

PF00069

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D6RG51

UniProt Splice Variant

Entrez Gene

26412

UniGene

Mm.397983

RefSeq

MGI ID

MGI Symbol

Map4k2

OMIM

CCDS

HPRD

IMGT

EMBL

AC127556

GenPept