Version 5.4
Mus musculus Protein: Pecam1
Summary
InnateDB Protein IDBP-536007.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pecam1
Protein Name platelet/endothelial cell adhesion molecule 1
Synonyms C85791; Cd31; Pecam; PECAM-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000122414
InnateDB Gene IDBG-213505 (Pecam1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002687 positive regulation of leukocyte migration
GO:0006928 cellular component movement
GO:0007266 Rho protein signal transduction
GO:0030334 regulation of cell migration
GO:0030837 negative regulation of actin filament polymerization
GO:0034097 response to cytokine
GO:0034259 negative regulation of Rho GTPase activity
GO:0042060 wound healing
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0030485 smooth muscle contractile fiber
GO:0045121 membrane raft
GO:0071944 cell periphery
Protein Structure and Domains
PDB ID MGI:97537
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1ARA9
UniProt Splice Variant
Entrez Gene 18613
UniGene Mm.488284
RefSeq
MGI ID
MGI Symbol Pecam1
OMIM
CCDS
HPRD
IMGT
EMBL AL603664
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca