Version 5.4
Mus musculus Gene: Pecam1
Summary
InnateDB Gene IDBG-213505.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pecam1
Gene Name platelet/endothelial cell adhesion molecule 1
Synonyms C85791; Cd31; Pecam; PECAM-1
Species Mus musculus
Ensembl Gene ENSMUSG00000020717
Encoded Proteins
IDBP-213507
platelet/endothelial cell adhesion molecule 1
IDBP-213509
platelet/endothelial cell adhesion molecule 1
IDBP-213511
platelet/endothelial cell adhesion molecule 1
IDBP-268025
platelet/endothelial cell adhesion molecule 1
IDBP-536007
platelet/endothelial cell adhesion molecule 1
IDBP-789931
platelet/endothelial cell adhesion molecule 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:106654217-106750628
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000103069 ENSMUSP00000099358
ENSMUST00000080853 ENSMUSP00000079664
ENSMUST00000068021 ENSMUSP00000067111
ENSMUST00000106796 ENSMUSP00000102408
ENSMUST00000135481
ENSMUST00000124958 ENSMUSP00000122414
ENSMUST00000183610 ENSMUSP00000138959
ENSMUST00000184424
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002687 positive regulation of leukocyte migration
GO:0006928 cellular component movement
GO:0007155 cell adhesion
GO:0007266 Rho protein signal transduction
GO:0030334 regulation of cell migration
GO:0030837 negative regulation of actin filament polymerization
GO:0034097 response to cytokine
GO:0034259 negative regulation of Rho GTPase activity
GO:0042060 wound healing
GO:0042523 positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030485 smooth muscle contractile fiber
GO:0045121 membrane raft
GO:0071944 cell periphery
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
mmu04670
Leukocyte transendothelial migration pathway
mmu05144
Malaria pathway
INOH
PID NCI
Cross-References
SwissProt Q08481
TrEMBL B1ARA9
UniProt Splice Variant
Entrez Gene 18613
UniGene Mm.343951 Mm.488284
RefSeq NM_001032378 XM_006532472 NM_008816 XM_006532467 XM_006532470 XM_006532476
OMIM
CCDS CCDS25558 CCDS25559
HPRD
IMGT
MGI ID MGI:97537
MGI Symbol Pecam1
EMBL AK169431 AL603664 BC008519 BC085502 CH466558 L06039
GenPept AAA16230 AAH08519 AAH85502 BAE41172 CAM18558 CAM18559 CAM18560 EDL34303 EDL34304 EDL34305
RNA Seq Atlas 18613

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca