Version 5.4
Mus musculus Protein: Luc7l2
Summary
InnateDB Protein IDBP-536098.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Luc7l2
Protein Name LUC7-like 2 (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000124010
InnateDB Gene IDBG-137467 (Luc7l2)
Protein Structure
UniProt Annotation
Function May bind to RNA via its Arg/Ser-rich domain.
Subcellular Localization Isoform 4: Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with SCNM1 and SNRNP70 in nuclear speckles.
Disease Associations
Tissue Specificity All isoforms are expressed in brain, kidney, heart, thymus, stomach, skeletal muscle, testis and spinal cord. {ECO:0000269PubMed:17656373}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 66 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003729 mRNA binding
Biological Process
GO:0006376 mRNA splice site selection
Cellular Component
GO:0005685 U1 snRNP
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID MGI:2183260
InterPro IPR004882 Luc7-related
PFAM PF03194
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TNC4
PhosphoSite PhosphoSite-Q7TNC4
TrEMBL Q3UUS9
UniProt Splice Variant
Entrez Gene 192196
UniGene Mm.487618
RefSeq NP_001164320
MGI ID
MGI Symbol Luc7l2
OMIM
CCDS CCDS51751
HPRD
IMGT
EMBL AC124762 AC161147 AF318301 AK138070 BC002314 BC056354 BC056383 BC056970
GenPept AAH02314 AAH56354 AAH56383 AAH56970 AAK01182 BAE23545

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca