InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Med24

Summary

InnateDB Protein

IDBP-536105.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Med24

Protein Name

mediator complex subunit 24

Synonyms

911GSE; AU040102; AW547152; D11Ertd307e; DRIP100; Gse2; Pparb2; Pparbp2; R75526; Thrap4; Trap100;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118820

InnateDB Gene

IDBG-210636 (Med24)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 58 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	58 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001104	RNA polymerase II transcription cofactor activity
GO:0003713	transcription coactivator activity
GO:0004402	histone acetyltransferase activity
GO:0004872	receptor activity
GO:0046966	thyroid hormone receptor binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0016573	histone acetylation
GO:0019827	stem cell maintenance
GO:0030521	androgen receptor signaling pathway
GO:0045893	positive regulation of transcription, DNA-templated
GO:0051291	protein heterooligomerization

Cellular Component

GO:0016592

mediator complex

Protein Structure and Domains

PDB ID

MGI:1344385

InterPro

IPR021429 Mediator complex, subunit Med24, N-terminal

PFAM

PF11277

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A6PW46

UniProt Splice Variant

Entrez Gene

23989

UniGene

Mm.400606

RefSeq

MGI ID

MGI Symbol

Med24

OMIM

CCDS

HPRD

IMGT

EMBL

AL590963

GenPept