InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ace2

Summary

InnateDB Protein

IDBP-536243.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ace2

Protein Name

angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

Synonyms

2010305L05Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123313

InnateDB Gene

IDBG-184519 (Ace2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001618	virus receptor activity
GO:0001948	glycoprotein binding
GO:0004175	endopeptidase activity
GO:0004180	carboxypeptidase activity
GO:0008237	metallopeptidase activity
GO:0008241	peptidyl-dipeptidase activity
GO:0017046	peptide hormone binding

Biological Process

GO:0003051	angiotensin-mediated drinking behavior
GO:0006508	proteolysis
GO:0009615	response to virus
GO:0032800	receptor biosynthetic process
GO:0045087	innate immune response (InnateDB)
GO:0046813	receptor-mediated virion attachment to host cell

Cellular Component

GO:0005615	extracellular space
GO:0009986	cell surface
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1917258

InterPro

IPR001548 Peptidase M2, peptidyl-dipeptidase A

PFAM

PF01401

PRINTS

PR00791

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6X479

UniProt Splice Variant

Entrez Gene

70008

UniGene

Mm.401881

RefSeq

MGI ID

MGI Symbol

Ace2

OMIM

CCDS

HPRD

IMGT

EMBL

AL671706

GenPept