InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Immp2l

Summary

InnateDB Protein

IDBP-536641.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Immp2l

Protein Name

IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)

Synonyms

AI853880; IMP2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116441

InnateDB Gene

IDBG-136987 (Immp2l)

Protein Structure

UniProt Annotation

Function

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008233	peptidase activity
GO:0008236	serine-type peptidase activity

Biological Process

GO:0001541	ovarian follicle development
GO:0006508	proteolysis
GO:0006627	protein processing involved in protein targeting to mitochondrion
GO:0007283	spermatogenesis
GO:0008104	protein localization
GO:0030728	ovulation

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042720	mitochondrial inner membrane peptidase complex