InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gtf2h4

Summary

InnateDB Protein

IDBP-536842.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gtf2h4

Protein Name

general transcription factor II H, polypeptide 4

Synonyms

AW545633; BTF2 p52; p44; p52; TFIIH;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124683

InnateDB Gene

IDBG-178785 (Gtf2h4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004003	ATP-dependent DNA helicase activity
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006289	nucleotide-excision repair
GO:0006366	transcription from RNA polymerase II promoter
GO:0006468	protein phosphorylation
GO:0032508	DNA duplex unwinding

Cellular Component

GO:0000439	core TFIIH complex
GO:0005634	nucleus
GO:0005675	holo TFIIH complex

Protein Structure and Domains

PDB ID

MGI:1338799

InterPro

IPR004598 Transcription factor TFIIH subunit p52/Tfb2

PFAM

PF03849

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E0CYM3

UniProt Splice Variant

Entrez Gene

14885

UniGene

Mm.405927

RefSeq

MGI ID

MGI Symbol

Gtf2h4

OMIM

CCDS

HPRD

IMGT

EMBL

CR974483

GenPept