InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hk1

Summary

InnateDB Protein

IDBP-537221.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hk1

Protein Name

hexokinase 1

Synonyms

BB404130; dea; Hk-1; Hk1-s; mHk1-s;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118601

InnateDB Gene

IDBG-157046 (Hk1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004340	glucokinase activity
GO:0004396	hexokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008865	fructokinase activity
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0019158	mannokinase activity

Biological Process

GO:0001678	cellular glucose homeostasis
GO:0005975	carbohydrate metabolic process
GO:0006096	glycolytic process
GO:0046835	carbohydrate phosphorylation
GO:0051156	glucose 6-phosphate metabolic process
GO:0061621	canonical glycolysis

Cellular Component

GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0005929	cilium
GO:0045121	membrane raft
GO:0097228	sperm principal piece

Protein Structure and Domains

PDB ID

MGI:96103

InterPro

IPR001312 Hexokinase
IPR022672 Hexokinase, N-terminal
IPR022673 Hexokinase, C-terminal

PFAM

PF00349
PF03727

PRINTS

PR00475

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3TTB4

UniProt Splice Variant

Entrez Gene

15275

UniGene

RefSeq

MGI ID

MGI Symbol

Hk1

OMIM

CCDS

HPRD

IMGT

EMBL

AC126428 AC145297 AK161466 CH466553

GenPept

BAE36411 EDL32108