InnateDB Protein
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IDBP-537332.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hnf4a
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Protein Name
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hepatic nuclear factor 4, alpha
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Synonyms
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HNF-4; Hnf4; Hnf4alpha; MODY1; Nr2a1; Tcf14;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000119479
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InnateDB Gene
|
IDBG-211899 (Hnf4a)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1604 interaction(s) predicted by orthology.
Experimentally validated |
Total |
17
[view]
|
Protein-Protein |
12
[view]
|
Protein-DNA |
5
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
1604 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0000979
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RNA polymerase II core promoter sequence-specific DNA binding
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GO:0003677
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DNA binding
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0003705
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RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
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GO:0005515
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protein binding
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GO:0008270
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zinc ion binding
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GO:0043565
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sequence-specific DNA binding
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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GO:0006366
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transcription from RNA polymerase II promoter
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GO:0006629
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lipid metabolic process
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GO:0007548
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sex differentiation
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GO:0010470
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regulation of gastrulation
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GO:0023019
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signal transduction involved in regulation of gene expression
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GO:0045893
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positive regulation of transcription, DNA-templated
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0060395
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SMAD protein signal transduction
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Cellular Component |
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PDB ID |
MGI:109128
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InterPro |
IPR001628
Zinc finger, nuclear hormone receptor-type
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PFAM |
PF00105
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PRINTS |
PR00047
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PIRSF |
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SMART |
SM00399
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
A2A5I4
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UniProt Splice Variant |
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Entrez Gene |
15378
|
UniGene |
Mm.202383
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RefSeq |
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MGI ID |
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MGI Symbol |
Hnf4a
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL591488
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GenPept |
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