InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gla

Summary

InnateDB Protein

IDBP-537595.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gla

Protein Name

galactosidase, alpha

Synonyms

Ags;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123098

InnateDB Gene

IDBG-171557 (Gla)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004557	alpha-galactosidase activity
GO:0005102	receptor binding
GO:0016936	galactoside binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0009311	oligosaccharide metabolic process
GO:0016139	glycoside catabolic process
GO:0046477	glycosylceramide catabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005764	lysosome
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

MGI:1347344

InterPro

IPR000111 Glycoside hydrolase, clan GH-D
IPR002241 Glycoside hydrolase, family 27
IPR017853 Glycoside hydrolase, superfamily

PFAM

PF02065

PRINTS

PR00740

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2BDV6

UniProt Splice Variant

Entrez Gene

11605

UniGene

RefSeq

MGI ID

MGI Symbol

Gla

OMIM

CCDS

HPRD

IMGT

EMBL

BX004852

GenPept